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Bethyl
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Proteintech
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Merck KGaA
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Santa Cruz Biotechnology
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Santa Cruz Biotechnology
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Proteintech
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Proteintech
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DIAGENODE DIAGNOSTICS
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Image Search Results
Journal: Journal of Pathology and Translational Medicine
Article Title: Implication of PHF2 Expression in Clear Cell Renal Cell Carcinoma
doi: 10.4132/jptm.2017.03.16
Figure Lengend Snippet: Plant homeodomain finger 2 (PHF2) expression in non-neoplastic renal tissue. PHF2 is expressed in the nucleus and cytoplasm of the proximal tubular epithelium and in the nucleus of the distal tubular epithelium and podocytes in the glomerulus. (A) Cortex. (B) Medulla.
Article Snippet:
Techniques: Expressing
Journal: Journal of Pathology and Translational Medicine
Article Title: Implication of PHF2 Expression in Clear Cell Renal Cell Carcinoma
doi: 10.4132/jptm.2017.03.16
Figure Lengend Snippet: Relationship between PHF2 expression and clinicopathological characteristics
Article Snippet:
Techniques: Expressing, Biomarker Discovery
Journal: Journal of Pathology and Translational Medicine
Article Title: Implication of PHF2 Expression in Clear Cell Renal Cell Carcinoma
doi: 10.4132/jptm.2017.03.16
Figure Lengend Snippet: Kaplan-Meier curves. Cancer-specific and progression-free survival according to plant homeodomain finger 2 (PHF2) expression.
Article Snippet:
Techniques: Expressing
Journal: Journal of Pathology and Translational Medicine
Article Title: Implication of PHF2 Expression in Clear Cell Renal Cell Carcinoma
doi: 10.4132/jptm.2017.03.16
Figure Lengend Snippet: Univariate and multivariate Cox regression analysis of cancer-specific and progression-free survival
Article Snippet:
Techniques: Biomarker Discovery, Expressing
Journal: Oncotarget
Article Title: The prognostic significance of nuclear expression of PHF2 and C/EBPα in clear cell renal cell carcinoma with consideration of adipogenic metabolic evolution
doi: 10.18632/oncotarget.19949
Figure Lengend Snippet: Clinicopathologic features of patients with ccRCC and correlation between nuclear PHF2 and C/EBPα expression and clinicopathologic parameters.
Article Snippet: Each polyclonal rabbit anti-PHF2 antibody (Novus Biologicals, Littleton, CO) and polyclonal rabbit
Techniques: Expressing
Journal: Oncotarget
Article Title: The prognostic significance of nuclear expression of PHF2 and C/EBPα in clear cell renal cell carcinoma with consideration of adipogenic metabolic evolution
doi: 10.18632/oncotarget.19949
Figure Lengend Snippet: Multivariate analysis of cancer-specific and progression-free survival with PHF2 and C/EBPα nuclear expression in 344 patients with ccRCC (Cox proportional hazard model).
Article Snippet: Each polyclonal rabbit anti-PHF2 antibody (Novus Biologicals, Littleton, CO) and polyclonal rabbit
Techniques: Expressing
Journal: Nature Communications
Article Title: The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
doi: 10.1038/s41467-018-04361-y
Figure Lengend Snippet: Liver-specific Phf2 overexpression causes quick-onset hepatosteatosis. a – h Mice, injected with either GFP or Phf2 overexpressing adenovirus, were studied 3 weeks later in the fed state. a Phf2 mice develop hepatic steatosis as shown by increased liver size and by oil red O staining of liver sections. Scale bars = 100 μm ( n = 10 per group). b Measurement of PKCε activity ( n = 6 per group). c Liver DAG content in the cytosol and at the plasma membrane ( n = 8 per group). d Relative expression of liver pro-inflammatory genes ( n = 10 per group). e Insulin tolerance test ( n = 10 per group). f Oral glucose tolerance test and insulin levels during the OGTT test ( n = 10 per group). g Western blot analysis of the PI3K/Akt signaling pathway in liver ( n = 20 per group). h Heatmap visualization of relative SFA, MUFA, and PUFA content in liver DAG, TG, and cholesterol ester species ( n = 10 per group). i – k Isolated primary hepatocytes overexpressing Phf2 and in which SCD1 expression was inhibited were incubated in the presence of palmitate (480 μM) for 24 h. i Representative western blots of the pro-inflammatory signaling pathway ( n = 4). j Percentage of hepatocyte SFA, MUFA and PUFA content in indicated culture conditions ( n = 3). k Representative western blot analysis of the PI3K/Akt signaling ( n = 4). All error bars represent mean ± SEM. Statistical analyses were made using unpaired t -test. * P < 0.01 GFP compared to Phf2, ** P < 0.05 GFP compared to Phf2. # P < 0.01 NCD compared to HFHS
Article Snippet: PKCε was immunoprecipitated from liver samples of GFP or Phf2 overexpressing mice using 0.5 μg of polyclonal rabbit anti
Techniques: Over Expression, Injection, Staining, Activity Assay, Clinical Proteomics, Membrane, Expressing, Western Blot, Isolation, Incubation